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Figure 6 | Arthritis Research & Therapy

Figure 6

From: Cartilage oligomeric matrix protein is involved in human limb development and in the pathogenesis of osteoarthritis

Figure 6

Ultrastructural in situ hybridization for cartilage oligomeric protein (COMP) mRNA of the area adjacent to the main defect of osteoarthritic tissue. (a) Strong staining for COMP mRNA (arrows) is seen in a type 2 cell; inset shows a higher magnification. (b) Strong staining for COMP mRNA (arrows) is seen in a type 1 cell. (c) Note that the gold particles (arrows) are found only in the cytoplasm at the rough endoplasmic reticulum. Bars, 0.3 μm in (a) and (b) and 0.25 μm in (c) and inset (a). n, nucleus.

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Arthritis Research & Therapy

ISSN: 1478-6362

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