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Table 1 [3H]Paroxetine binding characteristics in platelet membranes of control subjects and patients with fibromyalgia

From: Alteration of serotonin transporter density and activity in fibromyalgia

Variable

Controls (n = 38)

Patients with FM (n = 40)

Bmax (fmol/mg protein)

1,260 ± 34

1,048 ± 30a

Kd (nM)

0.077 ± 0.012

0.086 ± 0.021

  1. Results are shown as means ± SEM. Bmax, maximal membrane binding capacity; FM, fibromyalgia; Kd, dissociation constant. ap < 0.0001.