From: The role of leptin in innate and adaptive immune responses
Diseases | Leptin levels: patients versus healthy controls | Correlation of leptin levels with disease activity | Comments | References |
---|---|---|---|---|
RA | Elevated | No correlation with CRP | No data on BMI | [91] |
RA | Elevated | Correlation with CRP | Different gender distribution in the groups | [92] |
RA | Similar | No correlation | Correlated with BMI and percentage of body fat | [94] |
RA | Similar | No correlation | Correlated with BMI | [95] |
RA | Similar | Negative correlation with CRP | No effect of short course anti-TNF-α therapy | [97] |
 |  | and IL-6 | on leptin levels |  |
RA | Reduced | No correlation | No correlation with BMI, CRP or total fat mass | [96] |
SLE | Elevated | No correlation | Correlated with BMI | [102] |
Systemic sclerosis | Reduced | No correlation | Correlated with BMI | [103] |
Behçet's disease | Elevated | Positive correlation | Gender ratio, age and BMI similar in patient and control groups | [104] |
Multiple sclerosis | Similar | Positive correlation | Leptin levels increased before exacerbation and decreased after treatment with IFN-β | [100] |
Multiple sclerosis | Similar | No correlation | Leptin levels increased in IFN-β treated patients during active disease and remission | [101] |