Figure 3

Gene Ontology analysis of the genes differentially expressed before and after treatment in the TNF-positive group of patients. The 20 most significant biological processes (Gene Ontology categories) and their parent terms are shown. The color of each node illustrates significance and can be interpreted in the scale bar, which displays the false discovery rate on a log₁₀ scale. The arrows indicate the parent to child direction. The numbers of each arrow demonstrate the amount of unique Entrez Gene IDs [57] among the DE genes that are mapped to the parent term, and the number of unique Entrez Gene IDs among all genes present on the chip that are mapped to the parent term.