Figure 5

Survival of MRL/lpr mice after transfer of Treg and CCR2-Treg cells. Mice were observed until day 160 or death. All experiments were carried out with groups of five mice. Similar results were obtained in one additional experiment. *P < 0.05 versus control by Student's t test. CCR2-Treg cell, CD4⁺CD25⁺Foxp3⁺ CCR2-transfected T cell; MRL/lpr, MRL/MpJ-lpr/lpr; Treg cell, CD4⁺CD25⁺Foxp3⁺ T cell.