Vasculopathy and disordered angiogenesis in selected rheumatic diseases: rheumatoid arthritis and systemic sclerosis

Table 1 Some proangiogenic mediators involved in the pathogenesis of rheumatoid arthritis

Type of molecule	Molecule
Growth factors	Fibroblast growth factor (FGF)-2
	Transforming growth factor (TGF)-β
	Hepatocyte growth factor (HGF)
	Vascular endothelial growth factors (VEGF, VEGF-C, and VEGF-D)
Cytokines	Tumour necrosis factor (TNF)-α
	Platelet activating factor (PAF)
	Angiopoietin (Ang)-1, Ang-2
Chemokines	Interleukin (IL)-8
	Epithelial neutrophil activating peptide (ENA)-78
	Growth related gene product (GRO)-α
	Stromal cell derived factor (SDF)-1
	Fractalkine
Other mediators	Endothelin (ET)-1

ISSN: 1478-6362