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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Human meniscus cells express hypoxia inducible factor-1α and increased SOX9 in response to low oxygen tension in cell aggregate culture

Figure 1

Gene expression of HIF-1α and target genes in the outer and inner meniscus. (a) Hypoxia inducible factor (HIF)-1α gene expression in the outer (O; white bars) and inner (I; black bars) region of meniscus tissue from three donors (n = 3). (b) Prolyl 4-hydroxylase (P4H)α(I) and HIF prolyl-hydroxylase (PHD)2 gene expression in the outer (O; white bars) and inner (I; black bars) region of meniscus tissue (n = 3). Values are expressed as mean ± standard deviation. *P < 0.05, **P < 0.01 (by Student's unpaired t-test) in inner versus outer region of the meniscus matched against the same donor.

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Arthritis Research & Therapy

ISSN: 1478-6362

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