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Figure 2 | Arthritis Research & Therapy

Figure 2

From: IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats

Figure 2

IL-23-induced formation of human osteoclasts from peripheral blood mononuclear cells (PBMC). PBMC were cultured in the presence of macrophage-colony stimulating factor (M-CSF) and recombinant human (rh)IL-23 (0.01, 0.1, 1.0, 10, 100, or 200 ng/ml) during the first 3 days. Adherent cells were then cultured with M-CSF alone during the last 7 days (days 4 to 10 (a–g) as indicated). Original magnification ×100.

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Arthritis Research & Therapy

ISSN: 1478-6362

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