Status | Subgroup | Genotype CT versus CC | Genotype TT versus CC | ||||
---|---|---|---|---|---|---|---|
 |  | OR | 95% CI | P | OR | 95% CI | P |
All | All | 0.80 | 0.66 to 0.97 | 0.02 | 1.04 | 0.67 to 1.62 | 0.86 |
 | Women | 0.94 | 0.75 to 1.17 | 0.56 | 1.01 | 0.60 to 1.71 | 0.97 |
 | Men | 0.50 | 0.35 to 0.73 | 0.0002 | 1.20 | 0.52 to 2.81 | 0.67 |
RF positive | All | 0.85 | 0.69 to 1.04 | 0.12 | 0.92 | 0.56 to 1.53 | 0.76 |
 | Women | 0.96 | 0.75 to 1.23 | 0.74 | 1.03 | 0.58 to 1.84 | 0.92 |
 | Men | 0.59 | 0.39 to 0.88 | 0.009 | 0.74 | 0.26 to 2.12 | 0.58 |
RF negative | All | 0.70 | 0.54 to 0.90 | 0.006 | 1.24 | 0.71 to 2.14 | 0.45 |
 | Women | 0.88 | 0.65 to 1.18 | 0.39 | 0.94 | 0.47 to 1.90 | 0.87 |
 | Men | 0.34 | 0.20 to 0.60 | 0.0001 | 2.03 | 0.88 to 5.29 | 0.15 |
Anti-CCP positive | All | 0.86 | 0.70 to 1.07 | 0.17 | 1.01 | 0.61 to 1.71 | 0.98 |
 | Women | 1.02 | 0.80 to 1.31 | 0.88 | 1.12 | 0.63 to 2.00 | 0.70 |
 | Men | 0.54 | 0.36 to 0.83 | 0.003 | 0.79 | 0.28 to 2.24 | 0.65 |
Anti-CCP negative | All | 0.69 | 0.54 to 0.89 | 0.004 | 1.07 | 0.62 to 1.84 | 0.82 |
 | Women | 0.82 | 0.61 to 1.10 | 0.19 | 0.86 | 0.43 to 1.73 | 0.67 |
 | Men | 0.4 | 0.2 to 0.7 | 0.0004 | 1.8 | 0.7 to 4.6 | 0.26 |