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Table 2 Demographic and baseline characteristics (intent-to-treat population)

From: Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study

Parameter

Placebo

25 mg

50 mg

100 mg

200 mg

 

(n = 77)

(n = 80)

(n = 79)

(n = 80)

(n = 79)

Age in years, mean (standard error of the mean)

62.0 (0.92)

62.4 (0.86)

62.6 (0.92)

62.9 (0.95)

63.1 (0.80)

Males, number (percentage)

23 (30%)

20 (25%)

18 (23%)

23 (29%)

30 (38%)

Females, number (percentage)

54 (70%)

60 (75%)

61 (77%)

57 (71%)

49 (62%)

Estrogen/SERM use among females, number (percentage)

     

   Yes

5 (9%)

9 (15%)

6 (10%)

5 (9%)

4 (8%)

   No

49 (91%)

51 (85%)

55 (90%)

52 (91%)

45 (92%)

  1. SERM, selective estrogen receptor modulator.