Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study

Table 3 Univariate analyses for cardiovascular morbidity in patients with rheumatoid arthritis in the QUEST-RA study

	Cardiovascular morbidity (percentage of patients)
	No	Yes	Hazard ratio	95% CI	P value
Rheumatoid variables
Rheumatoid factor	71.7	77.0	1.02	0.76–1.37	0.881
Extra-articular disease^a	23.0	43.3	1.52	1.19–1.95	0.001
Traditional risk factors
Age in years (mean)	55.8	66.4	1.05	1.04–1.06	0.000
Gender (female)	79.4	64.0	0.42	0.33–0.54	0.000
Hypertension	28.7	62.9	2.97	2.31–3.83	0.000
Hyperlipidemia	11.3	34.0	3.19	2.47–4.13	0.000
Diabetes	6.9	15.8	2.09	1.50–2.92	0.000
Smoking ever	42.6	51.2	1.60	1.25–2.04	0.000
Smoking now	18.3	11.8	0.80	0.55–1.18	0.260
Obesity	17.5	18.3	1.34	0.96–1.86	0.082
Physical inactivity	71.9	73.5	1.00	0.75–1.33	0.993

^aIncludes nodules, pulmonal fibrosis, pericarditis, vasculitis, Felty syndrome, and scleritis. CI, confidence interval; QUEST-RA, Questionnaires in Standard Monitoring of Patients with Rheumatoid Arthritis.

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