From: Biology and therapy of fibromyalgia. Evidence-based biomarkers for fibromyalgia syndrome
Reference | Year of study | Number of FM patients | Number of control individuals | QST | QST method | Findings |
---|---|---|---|---|---|---|
Petzke and colleagues [28] | 2003 | 43 | 28 | HPT, suprathreshold | ASC and RAN | FM decreased HPT, suprathresholds. Pain ratings from RAN were consistently higher than ASC, possibly due to perceived lack of perceived control |
Gibson and colleagues [29] | 1994 | 10 | 10 | WT and HPT | ASC and RAN | FM decreased HPT, no difference in WT |
Staud and colleagues [102] | 2005 | 11 | 12 | Suprathreshold: affected and CP | ASC | Increased thermal pain ratings after exercise (opposite of HC) |
Geisser and colleagues [108] | 2003 | 20 | 20 | HPT, WT | ASC | FM with decreased HPT. Higher intensity and unpleasantness for non-noxious stimuli |
Kosek and Hansson [30] | 1997 | 10 | 10 | CT, WT, CPT, HPT | ASC | FM decreased CT in forearm. FM decreased CPT and HPT. No difference in WT |
Lautenbacher and Rollman [34] | 1997 | 25 | 26 | HPT | ASC | FM had decreased HPT |
Kosek and colleagues [31] | 1996 | 10 | 10 | CT, WT, CPT, HPT | ASC | FM decreased HPT, CPT. FM had decreased WT only at TP |
Lorenz and colleagues [128] | 1996 | 10 | 10 | HPT | ASC | FM decreased HPT |
Lautenbacher and colleagues [120] | 1994 | 26 | 26 | HPT | ASC | FM decreased HPT, no difference in WT |
Lautenbacher and Rollman [34] | 1997 | 25 | 26 | Electrical | ASC | No difference in electrical detection/PT |
Lautenbacher and colleagues [120] | 1994 | 26 | 26 | Electrical – CP and TP | ASC | FM decreased electrocutaneous only at TP, not control points |
Arroyo and Cohen [129] | 1993 | 10 | 10 | Electrical detection, suprathreshold | ASC | No difference in electrical detection, FM decreased electrical tolerance |