Gene | SNP | Genotypes | RA (n [%]) | Controls (n [%]) | OR (95% CI) | P value |
---|---|---|---|---|---|---|
IL-13 | rs1800925 | TT | 26 (2.9) | 26 (2.8) | 1.0 (0.6–1.9) | 0.9 |
CT | 271 (29.9) | 276 (29.6) | 1.0 (0.8–1.3) | 0.9 | ||
CC | 608 (67.2) | 631 (67.6) | 1.0 | |||
rs1295686 | TT | 26 (3.0) | 31 (3.3) | 0.9 (0.5–1.6) | 0.7 | |
CT | 251 (29.3) | 283 (30.4) | 0.9 (0.8–1.2) | 0.6 | ||
CC | 580 (67.7) | 617 (66.3) | 1.0 | |||
IL-4 | rs2227284 | AA | 56 (6.1) | 47 (4.9) | 1.2 (0.8–1.9) | 0.3 |
AC | 316 (34.6) | 349 (36.7) | 0.9 (0.8–1.1) | 0.4 | ||
CC | 541 (59.3) | 554 (58.3) | 1.0 | |||
rs2243263 | CC | 8 (0.9) | 6 (0.6) | 1.4 (0.4–4.8) | 0.6a | |
GC | 146 (16.4) | 166 (17.9) | 0.9 (0.7–1.2) | 0.4 | ||
GG | 738 (82.7) | 753 (81.4) | 1.0 | |||
rs2243267 | CC | 18 (2.0) | 17 (1.8) | 1.1 (0.5–2.3) | 0.8a | |
CG | 218 (24.0) | 205 (22.2) | 1.1 (0.9–1.4) | 0.4 | ||
GG | 672 (74.0) | 702 (76.0) | 1.0 | |||
IL-4R | rs1805010 | GG | 198 (21.8) | 200 (21.3) | 1.2 (0.9–1.5) | 0.2 |
AG | 460 (50.7) | 438 (46.6) | 1.3 (1.0–1.6) | 0.03 | ||
AA | 250 (27.5) | 301 (32.1) | 1.0 | |||
rs1801275 | AA | 38 (4.2) | 41 (4.3) | 1.0 (0.6–1.6) | 1.0 | |
AG | 316 (34.6) | 302 (32.0) | 1.1 (0.9–1.4) | 0.2 | ||
GG | 558 (61.2) | 601 (63.7) | 1.0 |