Table 4 Genotype frequencies of the genes involved in the IL-4/IL-13 pathway and modified Larsen score
Gene | SNP | Genotypes | Patients (n) | Median LSa | P |
|---|---|---|---|---|---|
IL-13 | rs1800925 | TT | 26 | 31.0 | |
CT | 271 | 27.0 | 0.8 | ||
CC | 608 | 28.0 | |||
rs1295686 | TT | 26 | 33.5 | ||
CT | 251 | 25.0 | 0.8 | ||
CC | 580 | 28.0 | |||
IL-4 | rs2227284 | AA | 56 | 27.0 | |
AC | 316 | 29.0 | 0.6b | ||
CC | 541 | 29.0 | |||
rs2243263 | CC | 8 | 41.5 | ||
AC | 146 | 26.0 | 0.3 | ||
AA | 738 | 28.0 | |||
rs2243267 | CC | 18 | 23.5 | ||
CG | 218 | 29.0 | 0.9 | ||
GG | 672 | 28.0 | |||
IL-4R | rs1805010 | GG | 198 | 24.5 | |
AG | 460 | 30.0 | 0.5 | ||
AA | 250 | 29.0 | |||
rs1801275 | AA | 38 | 28.0 | ||
AG | 316 | 27.5 | 0.5 | ||
GG | 558 | 29.0 |