Figure 7From: Disruption of the thrombospondin-2 gene alters the lamellar morphology but does not permit vascularization of the adult mouse lumbar discLocation of small blood vessels along the margin of the ventral portion of the annulus. Small blood vessels were visualized with platelet endothelial cell adhesion molecule-1 immunohistochemistry (red localization product). (a) Modest vasculature is present in the tissues near the disc in the wild-type (WT) mouse. (b) In the thrombospondin-2-null mouse, a much larger vascular bed is present. Magnification, ×500.Back to article page