Skip to main content

Table 4 Framingham analysis: independent association of standardized biomarkers with BML (BML > 0) per SD of change in marker

From: Biochemical markers of bone turnover and their association with bone marrow lesions

Marker

Adjusted for age, sex, and BMI

Multi-adjusted (adjusted for age, sex, BMI, and BMD)

Multi-adjusted (Adjusted for OA, age, sex, BMI, and BMD)

Ln-BSAP

1.4 (0.9 to 2.1)

1.4 (0.9 to 2.0)

1.26 (0.75 to 2.11)

Ln-osteocalcin

1.1 (0.7 to 1.7)

1.1 (0.7 to 1.7)

1.60 (0.99 to 2.57)

Ln-NTx

1.7 (1.1 to 2.7)

1.7 (1.1 to 2.6)

1.65 (0.96 to 2.83)

  1. Values are presented as odds ratio (95% confidence interval). BML, bone marrow; BSAP, bone-specific alkaline phosphatase; Ln, Natural Log; NTx, type I collagen N-telopeptide; SD, standard deviation.