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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Mapping similarities in mTOR pathway perturbations in mouse lupus nephritis models and human lupus nephritis

Figure 4

Expression changes in transcripts associated with disease progression. Scatter plot showing the expression levels of dysregulated probe sets expressed in (NZBxNZW)F1 kidneys of mice with lupus nephritis (older mice) (Y axis) compared with expression levels in asymptomatic (younger) mice (X axis). (a) Expression levels of 547 non-immunoglobulin (Ig) probe sets significantly associated with disease, 46% of which are expressed at higher levels in diseased kidney. (b) Expression levels of 195 immunoglobulin probes sets, 100% of which are expressed at higher levels in diseased kidney.

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