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Table 4 Subset analysis showing genetic association between clinical subsets of patients with Behçet's disease compared with normal healthy controls

From: Identification of novel genetic susceptibility loci for Behçet's disease using a genome-wide association study

Clinical subset

SNP

Associated allele

OR

95% confidence interval

P value

    

LL

UL

 

Eye disease present

rs11206377

G

1.81

1.13

2.90

0.0125

 

rs2061634

G

1.82

1.14

2.89

0.011

 

rs317711

C

2.31

1.34

3.98

0.0023

 

rs4936742

T

2.17

1.37

3.44

0.0008

 

rs9513584

G

1.05

0.65

1.69

0.8403

Eye disease absent

rs11206377

G

1.96

1.33

2.89

0.0007

 

rs2061634

G

2.26

1.54

3.33

3.01 × 10-5

 

rs317711

C

2.26

1.41

3.63

0.0006

 

rs4936742

T

1.40

0.96

2.04

0.0823

 

rs9513584

G

1.97

1.34

2.88

0.0005

Vascular disease present

rs11206377

G

2.01

1.18

3.40

0.009

 

rs2061634

G

1.47

0.88

2.46

0.1385

 

rs317711

C

2.20

1.21

3.99

0.0087

 

rs4936742

T

2.04

1.23

3.36

0.0049

 

rs9513584

G

1.74

1.05

2.86

0.0292

Vascular disease absent

rs11206377

G

1.86

1.29

2.70

0.001

 

rs2061634

G

2.35

1.62

3.43

6.22 × 10-6

 

rs317711

C

2.25

1.42

3.57

0.0004

 

rs4936742

T

1.54

1.07

2.21

0.0209

 

rs9513584

G

1.52

1.04

2.20

0.0281

Both eye and vascular disease present

rs11206377

G

3.11

1.29

7.47

0.0082

 

rs2061634

G

1.37

0.66

2.88

0.3987

 

rs317711

C

3.29

1.52

7.12

0.0015

 

rs4936742

T

2.39

1.14

5.02

0.0184

 

rs9513584

G

1.24

0.60

2.59

0.5585

Neither eye nor vascular disease present

rs11206377

G

2.10

1.36

3.24

0.0007

 

rs2061634

G

2.59

1.70

3.95

7.16 × 10-6

 

rs317711

C

2.50

1.51

4.14

0.0003

 

rs4936742

T

1.30

0.86

1.98

0.2123

 

rs9513584

G

1.84

1.21

2.79

0.0042

  1. LL, lower limit; OR, odds ratio; SNP, single-nucleotide polymorphism; UL, upper limit.