| LN-GMT (n = 25) | LN-non-GMT (n = 99) | P value |
---|---|---|---|
Sex (male/female) | 3/22 | 16/83 | 0.837 |
Age (years) | 35 ± 14 | 33 ± 14 | 0.485 |
SLE duration (months) | 48 (8 to 126) | 19 (4 to 69.5) | 0.096 |
LN duration (months) | 19 (1 to 78) | 4.5 (1–24) | 0.101 |
SLEDAI | 17 ± 6 | 12 ± 6 | 0.002 |
Proteinuria (g/24 hours) | 3.24 (2.22 to 4.66) | 2.01 (1.19 to 3.66) | 0.005 |
Serum creatinine (μmol/L) | 99.7(67.85 to 118.5) | 59.6(49.08 to 82.75) | <0.001 |
Blood urea nitrogen (mmol/L) | 11.3 (6.05 to 15) | 6.4 (4.9 to 10) | 0.007 |
Serum C3 (g/L) | 0.44 ± 0.23 | 0.62 ± 0.26 | 0.003 |
Serum C4 (g/L) | 0.09 (0.06 to 0.17) | 0.10 (0.05 to 0.17) | 0.717 |
Serum C1q (g/L) | 0.38 (0.34 to 0.43) | 0.33 (0.29 to 0.40) | 0.092 |
ANA (positive/negative)†| 20/3 | 82/8 | 0.837 |
Anti-Sm (positive/negative) | 3/20 | 32/58 | 0.037 |
Anti-RNP (positive/negative) | 4/19 | 34/56 | 0.065 |
Anti-dsDNA (positive/negative)‡ | 20/5 | 67/29 | 0.312 |
Anti-nucleosome(positive/negative)¶ | 10/6 | 21/25 | 0.246 |
Anti-histone (positive/negative)§ | 10/5 | 30/19 | 0.703 |