The utility of MRI in predicting radiographic erosions in the metatarsophalangeal joints of the rheumatoid foot: a prospective longitudinal cohort study

Table 1 Magnetic resonance imaging (MRI) erosions predicting subsequent radiographic erosions and MRI bone marrow edema predicting subsequent MRI erosions

MRI erosions predicting subsequent radiographic erosions
Time interval between studies	Patients	New x-ray erosions preceded by MRI erosion	MRI erosions NOT leading to x-ray erosion	New x-ray erosion NOT preceded by MRI erosion	Studies not having an x-ray or MRI erosion	Sensitivity	Specificity	PPV	NPV	Odds ratio (CI)
6 months	43	3	32	1	430	0.75	0.93	0.086	0.998	^a40.3 (4.08–398.7)
12 months	39	3	27	2	417	0.6	0.94	0.10	0.995	^a32.2 (3.7–144.6)
24 months	41	3	15	1	218	0.75	0.94	0.17	0.995	^a43.6 (4.27–445)
MRI bone marrow edema predicting subsequent MRI erosions
Time interval between studies	Patients	New MRI erosions preceded by BME	BME NOT leading to MRI erosion	New MRI erosion NOT preceded by BME	Studies not having an MRI erosion or BME	Sensitivity	Specificity	PPV	NPV	Odds ratio (CI)
6 months	43	4	12	4	410	0.50	0.97	0.25	0.99	^a34.17 (7.62–153.1)
12 months	39	6	6	3	204	0.67	0.97	0.50	0.99	^a68.0 (13.6–338.9)

The data for the major endpoints of the study are summarized here. The number of patients at each time interval varies because not all patients completed all studies. All radiographic erosions not preceded by an MRI erosion were preceded by MRI defects. There were only five new radiographic erosions for the entire cohort. ^aStatistically significant. BME, bone marrow edema; CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value.

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