Table 5 Time to first response (days) in intention-to-treat population, according to initial masitinib dosage
Parameter | 3 mg/kg per day (n = 22) | 6 mg/kg per day (n = 18) | Total population (n = 40) | P value |
|---|---|---|---|---|
ACR20 | ||||
Patients | 12/22 (55.0%) | 11/18 (61.0%) | 23/40 (57.5%) | 0.213 |
Mean ± SD | 51.9 ± 24.5 | 40.3 ± 19.0 | 46.3 ± 22.4 | |
Median | 56.0 | 29.0 | 35.0 | |
Range | 28.0–105.0 | 28.0–86.0 | 28.0–105.0 | |
ACR50 | ||||
Patients | 7/22 (32.0%) | 8/18 (44.0%) | 15/40 (37.5%) | 0.771 |
Mean ± SD | 91.9 ± 59.5 | 86.8 ± 61.1 | 89.1 ± 58.2 | |
Median | 84.0 | 72.5 | 84.0 | |
Range | 28.0–217.0 | 28.0–203.0 | 28.0–217.0 |