| Controls (n = 216) | Scleroderma patients (n = 444) |
---|---|---|
Age (years) | 51 ± 14 years | 53 ± 12.1 |
Gender | Â | Â |
   Male | 117 (54%) | 56 (13%) |
   Female | 99 (46%) | 388 (87%) |
Scleroderma phenotype | Â | Â |
   Limited |  | 241 (54%) |
   Diffuse |  | 200 (45%) |
Disease duration (years) |  | 6.9 ± 0.3 |
Systemic sclerosis-association autoantibodies | Â | Â |
   Anti-centromere |  | 109 (25%) |
   Anti-topoisomerase |  | 112 (25%) |
   Anti-RNA polymerase III |  | 109 (25%) |