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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs

Figure 3

Cytoplasmic localization of matrix metalloproteinase 28 in cells of the inner annulus and nucleus pulposus. (a) Cytoplasmic localization of matrix metalloproteinase (MMP) 28 in cells of the inner annulus of a Thompson Grade III disc. Note the negative cells (arrows) that lie near a cell with positive expression. (b) Inner annulus cells in clusters in a Thompson Grade III disc. Note the presence of both positive and negative (arrows) cells. (c) Some, but not all, cells show MMP28 localization in the nucleus pulposus of this Thompson grade IV disc. Magnification: (a) ×400, (b) ×580, (c) ×360.

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Arthritis Research & Therapy

ISSN: 1478-6362

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