The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity

Table 1 Studies documenting the detrimental effects of IFN-γ in murine systemic lupus erythematosus

Strain	Experimental manipulations	References
(CBA × C57/BL10)F1	trIFN-γ	[29,30]
B × W	IFN-γ	[38,39]
B × W	Anti-IFN-γ mAb	[38]
B × W	sIFN-γR	[39]
B × W	IFN-γR^-/-	[43]
MRL-Fas^lpr	sIFN-γR/Fc	[47]
MRL-Fas^lpr	IFN-γ^-/-	[41,42]
MRL-Fas^lpr	IFN-γR^-/-	[44]

ISSN: 1478-6362