Figure 2

Correlation of Th17 and Th1 response is dysregulated in patients with SLE. (a) The frequency (% of CD4⁺IL-17⁺ T cells correlates with the frequency of CD4⁺IFN-γ⁺ T cells in healthy control subjects (HC, n = 26) but not in patients with SLE (n = 25). (b) Patients with SLE have a higher Th17/Th1 ratio (frequency of CD4⁺IL-17⁺ T cells/frequency of CD4⁺IL-IFN-γ⁺ T cells) compared with healthy control subjects. Bars and numbers in (b) indicate the means.