| Univariate1 | Multivariate2 |
---|
Variable | Beta (β) | P value | HR (95%CI) | Beta (β) | P value | HR (95%CI) |
---|
RF positive
| 0.114 | 0.328 | 1.121 (0.892-1.408) | Â | Â | Â |
Male gender
| -0.641 | 0.000 | 0.527 (0.433-0.641) | -0.511 | 0.000 | 0.600 (0.469-0.767) |
Age
| -0.009 | 0.008 | 0.991 (0.984-0.998) | -0.007 | 0.047 | 0.993 (0.986-0.999) |
Baseline DAS
| -0.364 | 0.000 | 0.695 (0.635-0.760) | -0.693 | 0.000 | 0.500 (0.434-0.576) |
Baseline HAQ
| -0.436 | 0.000 | 0.647 (0.529-0.791) | Â | Â | Â |
Dis duration
| -0.005 | 0.217 | 0.995 (0.987-1.003) | Â | Â | Â |
44 SJC
| -0.018 | 0.007 | 0.982 (0.969-0.995) | Â | Â | Â |
53 TJC
| -0.057 | 0.000 | 0.945 (0.932-0.958) | Â | Â | Â |
ESR
| -0.004 | 0.048 | 0.996 (0.992-0.999) | Â | Â | Â |
VAS GH
| -0.017 | 0.000 | 0.983 (0.978-0.987) | Â | Â | Â |
- 1 Results of univariate Cox proportional hazard models with baseline predictors for time-to-DAS remission (disease activity score, DAS<1.6) up to three years of follow-up, given with hazard ratios (HR) and 95% confidence intervals (95%CI). 2 Results of the final multivariate Cox proportional hazard prediction model with independent baseline predictors for the time-to-remission (disease activity score, DAS<1.6) up to three years of follow-up, given with hazard ratios (HR) and 95% confidence intervals (95%CI).
- RF = rheumatoid factor; DAS = disease activity score based on 53 tender joint counts (TJC) and 44 swollen joint counts (SJC); HAQ = health assessment questionnaire; Dis = disease; ESR = erythrocyte sedimentation rate; VAS = visual analogue scale; GH = general health. Age was measured in years and disease duration in weeks.