Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins

Table 2 Immunodetection of selected antigens in IC obtained from SF of individual RA CCP+ and CCP- patients

	Patient n° (RF;CCP)	Fibβ	Fibγ	Vimentin
RA CCP-	SF1 (6;0)	+	+	+
	SF2 (80;1)	+	+	-
	SF3 (0;1)	+	+	-
	SF4 (0;1,6)	+	+	+
	SF5 (0;2)	+	+	+
	SF6 (5;2)	+	+	+
	SF7 (0;3)	+	+	+
	SF8 (40;4)	+	-	-
	SF9 (0;5)	+	+	-
	SF10 (0;5)	+	-	-
	SF11 (80;7)	+	+	+
	SF12 (160;10)	+	+	-
RA CCP+	SF13 (351;107)	+*	-	+
	SF14 (183;340)	+	-	+
	SF15 (1,280;533)	+	-	+*
	SF16 (1,280;608)	+	+	+*
	SF17 (1,280;710)	+	+	+
	SF18 (2,560;740)	+	+	+
	SF19 (10,240;767)	+	+	weak
	SF21 (640;1294)	+	+	+
	SF22 (0;1,600)	+	+	+*
	SF23 (160;1,600)	+	+	+*
	SF24 (0;1,600)	+	+	+
	SF25 (640;1,775)	+	+	+*
SpA	SF27 (0;0)	+	-	-
	SF28 (ND;1,6)	+	+	+
	SF29 (0;2)	+	+	+
	SF30 (0;2)	+	+	+
	SF31 (0;3)	+	+	+
	SF32 (0;4)	+	+	-
	SF33 (0;11)	+	+	-
	SF34 (0;ND)	+	+	-
	SF35 (ND;ND)	+	+	-
	SF36 (0;ND)	+	-	+
	SF37 (0;ND)	+	-	+
	SF38 (0;ND)	+	+	+

(+) Indicates the positive immunodetection; (-) indicates absence of the positive antibody staining and (*) indicates that the antigen was citrullinated as confirmed by AMC staining. ND, not determined

ISSN: 1478-6362