Figure 3From: Abnormalities of T cell signaling in systemic lupus erythematosusSchematic showing the CD3 ζ gene. Genomic DNA with eight exons (top), the mRNA with a full-length 906-bp 3' UTR (WT; middle) and the 344-bp alternatively spliced (AS) 3' UTR variant (bottom). SLE T cells express increased amounts of the unstable AS splice variant relative to the stable WT isoform.Back to article page