Figure 1

Radiological Larsen score progression over time after stratification according to the median (-0.0185 g/cm²per year) of early bone mineral density measured by digital X-ray radiogrammetry (DXR-BMD) change. High loss (black solid line) versus low loss (red dotted line) of DXR-BMD. Values are given as means with 95% confidence intervals (95% CIs). The larger 95% CIs at 15 and 20 years illustrate the decreasing number of patients at these time points.