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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Protein synthesis of the pro-inflammatory S100A8/A9 complex in plasmacytoid dendritic cells and cell surface S100A8/A9 on leukocyte subpopulations in systemic lupus erythematosus

Figure 1

Increased cell surface S100A8/A9 in patients with active disease compared with inactive disease and healthy controls. The cell surface S100A8/A9 was determined by flow cytometry on A) CD14++CD16+, B) CD14++CD16-, C) CD3+, D) CD19+, E) CD16+ PMNs, F) BDCA-1+ and G) BDCA-2+ cells. The expression is defined as the mean fluorescence index (MFI) ratio between the S100A8/A9 antibody and its control isotype antibody in each experiment. The line represents the median-value. Active disease was defined as SLEDAI > 4 (SLE active).

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