Gout | Controls | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Characteristics | Māorib | EPb | WP | NZ Caucasian | FHS | ARIC | Māori | NZ EP | NZ WP | NZ Caucasian | FHS | ARIC |
Number of cases/controls | 229 | 261 | 187 | 327 | 67 | 153 | 343 | 348 | 142 | 638 | 47,12 | 6,969 |
Males, % | 78 | 76 | 95 | 85 | 94 | 73 | 31 | 33 | 57 | 42 | 45 | 45 |
Mean ± 1 SD grandparents of stated ancestry | 2.87 ± 1.15 | 3.10 ± 1.07 | 3.72 ± 0.59 | 4.00 ± 0.00 | - | - | 2.33 ± 1.20 | 2.46 ± 1.22 | 3.49 ± 0.86 | 4.00 ± 0.00 | - | - |
Mean serum urate at recruitment, mmol/L (range) | 0.45 (0.21 to 0.98) | 0.47 (0.19 to 0.98) | 0.49 (0.17 to 0.72) | 0.41 (0.18 to 1.07) | 0.42 (0.21 to 0.58) | 0.42 (0.11-0.70) | - | - | - | - | 0.29 (0.07 to 0.63) | 0.34 (0.03 to 0.72) |
Confirmed tophi, % | 38 | 39 | 56 | 30 | - | - | - | - | - | - | - | - |
Mean age at onset, years (range) | 39 (15 to 74) | 39 (15 to 74) | 34 (15 to 75) | 47 (15 to 83) | - | - | - | - | - | - | - | - |
Mean age at recruitment, years (range) | - | - | - | - | 38 (18 to 55) | 54 (45-65) | 44 (17 to 80) | 44 (17 to 85) | 38 (17 to 86) | 52 (17 to 95) | 37 (5 to 72) | 54 (44 to 66) |
Mean gout attacks in past year, n (range) | 11 (0 to > 1/week) | 11 (0 to > 1/week) | 16 (0 to > 1/week) | 7.5 (0 to > 1/week) | - | - | - | - | - | - | - | - |
First-degree relative with gout, % | 63 | 64 | 53 | 42 | - | - | 30 | 31 | 23 | 14 | - | - |
Allopurinol treatment, % | 83 | 82 | 87 | 78 | - | - | - | - | - | - | - | - |
Probenecid treatment, % | 6 | 6 | 13 | 6 | - | - | - | - | - | - | - | - |
Mean BMI (range) | 35 (22 to 62) | 35 (22 to 66) | 38 (22 to 93) | 30 (19 to 62) | 29 (20 to 37) | 28 (21-41) | 32 (20 to 77) | 32 (20 to 77) | 35 (21 to 63) | 28 (19 to 56) | 27 (15 to 61) | 27 (15 to 56) |
Type 2 DM, % | 28 | 30 | 18 | 13 | 15 | 7 | 10 | 9 | 11 | 7 | 4 | 7 |
Hypertension, % | 63 | 63 | 46 | 49 | - | - | 16 | 16 | 17 | 14 | - | - |
Dyslipidemia, % | 51 | 52 | 53 | 48 | - | - | 12 | 12 | 11 | 16 | - | - |
Cardiovascular disease, % | 40 | 38 | 20 | 37 | - | - | 3 | 3 | 1 | 6 | - | - |
Renal disease, % | 30 | 30 | 22 | 22 | 21 | - | 2 | 2 | 1 | 2 | 6 | - |