Figure 5From: Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokinesThe percentage of GAG loss in six days (A) and proteoglycan biosynthesis measured from days 4 to 6 in bovine cartilage in response to TNFα, DEX and glucocorticoid receptor antagonist, RU 486 (B). RU reversed the effect of DEX in sulfate incorporation. In each condition, n = 5 cartilage disks. * = P < 0.05 (only selected comparisons are shown). DEX, dexamethasone; GAG, glycosaminoglycans; RU486, a glucocorticoid receptor antagonist; TNFα, tumor necrosis factor alpha.Back to article page