Transcription factor | Normal | pSS |
---|
NF-IL6 | 100.0 ± 16.0 | 623.6 ± 85.8*** |
NF-IL6β | 100.0 ± 18.5 | 252.8 ± 51.5* |
NF-κB1 | 100.0 ± 11.4 | 167.5 ± 23.4* |
NF-κB2 | 100.0 ± 14.9 | 342.6 ± 45.4*** |
- pSS = primary Sjögren's syndrome. Total RNAs were extracted from monocytes prepared as described in the Table 2 footnote, and the expression levels of NF-IL6, NF-IL6β, NF-κB1 and NF-κB2 were quantitated. The relative expression levels of the genes are indicated. Data represent means ± SEM. Asterisk denotes statistically significant difference between "Normal" and "pSS." *P < 0.05 and ***P < 0.001.