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Figure 6 | Arthritis Research & Therapy

Figure 6

From: Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis

Figure 6

Micro-CT coronal images of tibia from a control knee (A) and a MIA-injected knee (C) at ten weeks post injection. Micro-CT images revealed the presence of marginal tibial osteophytes in all the rats in the MIA-injected knee (C, arrow), whereas the control knee injected with saline showed no osteophyte-like structure formation (A). The normal control tibia (B) and the marginal tibial osteophytes in the MIA-injected knee (D, arrow) were confirmed by histology at ten weeks post injection. The osteophytes contained marrow spaces filled with fibrous bone marrow cells. Original magnification × 40. Micro-CT, micro-computed tomography; MIA, monosodium iodoacetate.

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Arthritis Research & Therapy

ISSN: 1478-6362

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