Skip to main content
Figure 8 | Arthritis Research & Therapy

Figure 8

From: Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis

Figure 8

Macroscopic images of a control tibia (A-C) and of a MIA-injected tibia (D-F), at ten weeks post injection. The control tibia (A) had no cartilage lesions on the medial compartment (M) and lateral compartment of the tibial plateau, whereas the MIA-injected tibia (D) had severe cartilage lesions on the medial tibial plateau (M). Fluorochrome images of the MIA-injected tibia showed accumulation of calcein and xylenol orange along the margins of the tibial plateau (E, F), suggesting osteophyte formation whereas there was no accumulation of fluorochrome labels along the margins of control tibia (B, C). MIA, monosodium iodoacetate.

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us