Figure 6
From: IL-10 signaling in CD4+ T cells is critical for the pathogenesis of collagen-induced arthritis
IL-10 signaling in T cells has no effect on type II collagen-specific antibody production. Serum samples from DBA/1J Wt or Tg mice (six mice in each group) were collected on days 0, 14, 21, 35 and 42 after collagen-induced arthritis induction, and collagen-specific antibodies (immunoglobulin G (IgG), IgG1 and IgG2a) were detected by ELISA. The results of one representative experiment are shown.