Time point | MCP-1 | IL-1β | TNF-α | VEGF | IL-6 | |||||
---|---|---|---|---|---|---|---|---|---|---|
 | Sensitized | Saline-injected | Sensitized | Saline-injected | Sensitized | Saline-injected | Sensitized | Saline-injected | Sensitized | Saline-injected |
Day 0 | 1.0 ± 0.2 | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.2 | 1.0 ± 0.4 | 1.0 ± 0.5 | 1.0 ± 0.1 | 1.0 ± 0.2 | 1.0 ± 0.2 | 1.0 ± 0.1 |
7 hours | 13.9a ± 5.4 | 1.5 ± 0.6 | 30.2a ± 4.7 | 1.1 ± 0.2 | 5.13a ± 2.4 | 1.2 ± 0.5 | 3.8a ± 0.5 | 1.1 ± 0.2 | 35.0a ± 8.5 | 2.1 ± 1.0 |
Day 1 | 5.9a ± 1.9 | 1.1 ± 0.2 | 49.6a ± 29.4 | 1.0 ± 0.2 | 11.7a ± 5.2 | 1.1 ± 0.6 | 20.0a ± 12.2 | 1.1 ± 0.3 | 12.2a ± 2.6 | 1.2 ± 0.3 |
Day 2 | 6.3a ± 2.5 | 1.2 ± 0.4 | 23.4a ± 2.0 | 1.5 ± 0.5 | 0.4 ± 0.3 | 1.3 ± 0.7 | 3.7a ± 0.6 | 1.1 ± 0.3 | 157.5a ± 21.2 | 1.2 ± 0.3 |
Day 3 | 7.2a ± 2.7 | 1.1 ± 0.2 | 11.0* ± 2.7 | 1.1 ± 0.2 | 0.7 ± 0.5 | 1.1 ± 0.6 | 2.0 ± 0.4 | 1.0 ± 0.2 | 58.2a ± 6.4 | 1.4 ± 0.6 |
Day 7 | 3.3a ± 0.7 | 1.0 ± 0.2 | 5.9 ± 2.3 | 1.1 ± 0.2 | 0.3 ± 0.2 | 1.2 ± 0.6 | 0.7 ± 0.3 | 1.0 ± 0.2 | 79.7a ± 42.2 | 1.1 ± 0.3 |
Day 14 | 3.2a ± 1.4 | 1.1 ± 0.2 | 2.3 ± 0.3 | 1.0 ± 0.1 | 0.8 ± 0.5 | 1.1 ± 0.5 | 0.7 ± 0.2 | 1.0 ± 0.1 | 28.7a ± 7.1 | 1.3 ± 0.5 |