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Table 5 Replication study: association of the TGFB1+868 heterozygous genotype with ischaemic heart disease in early rheumatoid arthritis patients stratified by ever smoking

From: Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study

Ischemic heart disease

Smoke/+868 TC

Negative

Positive

OR (95% CI)

-/-

25 (92.6%)

2 (7.4%)

1.0 (referent)

-/+

38 (95.0%)

2 (5.0%)

0.66 (0.11-4.10)

+/-

69 (94.5%)

4 (5.5%)

0.66 (0.13-3.31)

+/+

67 (81.7%)

15 (18.3%)

2.34 (0.57-9.61)

   

AP: 0.84 (0.14-1.53)

  1. 'Negative' and 'positive' values are presented as number (percentage). AP, the attributable proportion due to interaction; CI, confidence interval; OR, odds ratio; TGFB1, transforming growth factor-beta-1.
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Arthritis Research & Therapy

ISSN: 1478-6362

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