| DNA sample | Women (%) | AIM frequency (%) | N/S score |
---|
Collectiona | Control | SLE | Control | SLE |
rs12913832
|
rs382259
|
rs6730157
| Â |
---|
NL | 180 | 104 | 59.4 | 86.5 | 83.0 | 77.6 | 72.5 | 100.0 |
BEb | 106 | 147 | 93.5 | 90.5 | Â | Â | Â | Â |
DE | 95 | 90 | n.a. | 90 | 77.9 | 68.1 | 56.9 | 80.5 |
CZb | 100 | 101 | 32 | 85.1 | Â | Â | Â | Â |
SK | 93 | 94 | 93.5 | 91.5 | 72.8 | 63.8 | 39.4 | 64.4 |
HU | 95 | 95 | 48.4 | 90.4 | 63.4 | 59.6 | 39.0 | 54.9 |
ES, LCG | 145 | 88 | 82.9 | 92 | 35.4 | 67.4 | 45.3 | 47.6 |
ES, OVD | 200 | 147 | 69 | 91.8 | 30.5 | 70.4 | 45.4 | 47.2 |
ES, SCQ | 95 | 109 | 48.4 | 96 | 35.1 | 68.2 | 41.3 | 46.0 |
ES, BCN | 97 | 90 | 52.6 | 91.1 | 32.6 | 63.2 | 41.6 | 40.5 |
ES, MAD | 281 | 92 | 68.8 | 91.3 | 33.1 | 61.9 | 42.3 | 40.0 |
PT | 97 | 100 | 91.3 | 95.3 | 28.7 | 60.7 | 39.1 | 34.6 |
IT, MXP | 106 | 129 | 42.5 | 86.8 | 47.6 | 49.1 | 19.8 | 26.2 |
IT, ROM | 102 | 84 | 55.9 | 89.7 | 38.2 | 51.9 | 15.3 | 20.3 |
GR, AUMS | 100 | 95 | 92 | 91.6 | 36.0 | 44.0 | 13.4 | 11.3 |
IT, NAP | 109 | 79 | 100 | 90.1 | 38.6 | 42.2 | 10.0 | 9.6 |
GR, EH | 100 | 98 | 67 | 86.7 | 36.7 | 38.0 | 13.5 | 6.8 |
- Collections are in descending order of N/S score. aCollections from: University Medical Center Groningen, The Netherlands (NL); Université Catholique de Louvain, Belgium (BE); Hannover Medical School, Germany (DE); Institute of Rheumatology, The Czech Republic (CZ); Martin Faculty Hospital, Slovakia (SK); Albert Szent-Györgyi Medical and Pharmaceutical Centre, Hungary (HU); Complexo Hospitalario Universitario A Coruña, Spain (ES, LCG); Hospital Universitario Central de Asturias, Spain (ES, OVD); Hospital Clinico Universitario de Santiago, Spain (ES, SCQ); Hospital Val d'Hebron of Barcelona, Spain (ES, BCN); Hospital 12 de Octubre, Madrid, Spain (ES, MAD); Hospital Garcia de Orta, Almada, Portugal (PT); University of Milan and Fondazione IRCCS Ospedale Maggiore Policlinico from Milan, Italy (IT, MXP), Ospedale S. Camillo - Forlanini from Roma, Italy (IT, ROM); Athens University Medical School, Athens, Greece (GR, AUMS); Second University of Naples, Italy (IT, NAP); and Evangelismos Hospital, Athens, Greece (GR, EH). bThese two collections were not analysed further because of differences in AIM frequencies between cases and controls.