| RAF (%) | RAF vs. N/S score | ||||
---|---|---|---|---|---|---|
SNP (locus) | Central European | Southern European | χ2 P value | r xy | Slope | P value |
rs3131379 (MSH5) | 14.9 | 4.6 | 4.9 × 10-26 | 0.92 | 4.15 | 2.0 × 10-6 |
rs2187668 (HLA-DQA1) | 15.7 | 8.7 | 1.9 × 10-9 | 0.88 | 4.93 | 4.0 × 10-5 |
rs2476601 (PTPN22) | 11.8 | 6.1 | 1.5 × 10-8 | 0.74 | 4.21 | 2.7 × 10-3 |
rs13277113 (C8orf13-BLK) | 31.0 | 23.2 | 2.2 × 10-6 | 0.20 | 0.95 | NS |
rs6445975 (PXK) | 29.0 | 22.6 | 7.5 × 10-5 | 0.66 | 2.67 | 0.01 |
rs1143679 (ITGAM) | 11.9 | 16.7 | 4.9 × 10-4 | -0.59 | -4.79 | 0.03 |
rs2205960 (TNFSF4) | 25.2 | 20.7 | 4.9 × 10-3 | 0.15 | 1.08 | NS |
rs1801274 (FCGR2A) | 44.5 | 48.6 | 0.03 | -0.40 | -1.25 | NS |
rs4963128 (KIAA1542) | 69.1 | 65.3 | 0.03 | 0.58 | 2.83 | 0.03 |
rs10488631 (IRF5) | 11.6 | 9.3 | 0.046 | 0.46 | 3.64 | 0.10 |
rs17435 (MECP2)a | 20.9 | 22.8 | NS | -0.57 | -2.84 | 0.03 |
rs573775 (ATG5) | 28.2 | 26.3 | NS | 0.51 | 4.10 | 0.06 |
rs7574865 (STAT4) | 23.3 | 23.8 | NS | -0.51 | -4.63 | 0.06 |
rs6920220 (TNFAIP3) | 19.3 | 17.8 | NS | 0.49 | 2.74 | 0.07 |
rs10798269 (1q25.1) | 66.2 | 69.0 | NS | -0.17 | -1.16 | NS |
rs5754217 (UBE2L3) | 22.8 | 20.8 | NS | 0.16 | 1.28 | NS |
rs2304256 (TYK2) | 73.1 | 71.0 | NS | 0.06 | 0.23 | NS |
rs2230926 (TNFAIP3) | 3.5 | 4.3 | NS | -0.21 | -3.42 | NS |
rs729302 (IRF5) | 67.8 | 69.0 | NS | -0.00 | -0.03 | NS |
rs17266594 (BANK1) | 71.2 | 70.9 | NS | 0.32 | 1.99 | NS |