Figure 3From: B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skinExpression of phosphorylated platelet-derived growth factor receptor in the papillary dermis following rituximab administration. Rituximab (RTX) mediates a significant attenuation in platelet-derived growth factor receptor (PDGFR) phosphorylation (activation) status. (A) Phospho-PDGFRα and (B) phospho-PDGFRβ expression is decreased following RTX administration.Back to article page