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Figure 3 | Arthritis Research & Therapy

Figure 3

From: B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin

Figure 3

Expression of phosphorylated platelet-derived growth factor receptor in the papillary dermis following rituximab administration. Rituximab (RTX) mediates a significant attenuation in platelet-derived growth factor receptor (PDGFR) phosphorylation (activation) status. (A) Phospho-PDGFRα and (B) phospho-PDGFRβ expression is decreased following RTX administration.

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