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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism

Figure 3

Effect of HA injection on cartilage histopathology in the TTR model. (A) Typical Safranin O histology of femoral and tibial epiphyses from naïve joints and joints of TTR and TTR+HA groups (B). For each of the experimental groups, the mean (+/SD) cartilage volume was calculated from the area stained with Safranin O as described in the Methods. The dotted lines show typical selections of areas used for cartilage quantitation.

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