Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism

Table 5 QPCR of mmp13 expression in cartilage/subchondral bone and meniscus/synovium

¹relative to gapdh, mean (SD) (Delta symbol) CT of 8 pools with 2 mice per pool for Naïve and 12 pools with 2 mice per pool for all 4 treatment groups.
²relative to gapdh, mean (SD) (Delta symbol) CT of 2 pools with 8 mice per pool for Naïve and 2 pools with 12 mice per pool for all 4 treatment groups. Values represent the average of the two pools, with the difference between duplicates being <20% of average pool value. p values: ³TTR vs Naive; ⁴TTR+HA or TTR+SA vs TTR; ⁵Fold Changes are relative to Naive.

ISSN: 1478-6362