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Figure 4 | Arthritis Research & Therapy

Figure 4

From: A novel autoantibody against fibronectin leucine-rich transmembrane protein 2 expressed on the endothelial cell surface identified by retroviral vector system in systemic lupus erythematosus

Figure 4

Inhibition test and epitope mapping. (A) Inhibition tests of binding activities to HUVECs were performed by using IgG from healthy donor (control) and anti-FLRT2 sera (X10-48) with soluble FLRT2 at the indicated concentrations. (B) Changes in binding activity to FLRT2 lacking the unique region (Δur) compared with native FLRT2 were analyzed by using anti-FLRT2 sera. Representative dot plot (left) and a summary of changes in each patient (right) are shown. Open circles show the binding activity to the intracellular FLRT2 domain.

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Arthritis Research & Therapy

ISSN: 1478-6362

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