From: Urine VCAM-1 as a marker of renal pathology activity index in lupus nephritis
 | Nonactive disease | Active disease | Total |
---|---|---|---|
Patients | 14 | 60 | 74 |
Age (years) | 37.5 (26.2 to 37.5) | 34.0 (28.0 to 40.0) | 35.0 (27.5 to 42.0) |
Female/male | 11/3 | 52/8 | 63/11 |
Race: African American, Hispanic, White | 7, 7, 0 | 26, 27, 7 | 33, 34, 7 |
SLEDAI | 2 (0 to 5.25) | 10 (4 to 17) | 10 (4 to 16) |
Renal SLEDAI | 0 | 8 (4 to 8) | 4 (4 to 8) |
Renal pathology | Â | Â | Â |
World Health Organization classification | Â | Â | |
   II | 4 | 8 | 12 |
   III | 1 | 16 | 17 |
   IV | 3 | 25 | 28 |
   V | 6 | 7 | 13 |
   Unknown | 0 | 3 | 3 |
Protein:creatinine ratio | 0.190 ± 0.040 | 1.536 ± 0.229* | 1.278 ± 0.195 |
Serum creatinine | 1.422 ± 0.403 | 1.738 ± 0.191 | 1.677 ± 0.172 |
Positive anti-dsDNA (total tested) | 4 (11) | 30 (50) | 34 (61) |
Hypocomplementemia (total tested) | 9 (11) | 35 (46) | 44 (57) |
Current medications | Â | Â | Â |
   Prednisone | 10 | 47 | 57 |
   Mycophenolic acid | 5 | 24 | 29 |
   Cyclophosphamide | 0 | 3 | 3 |
   Azathioprine | 2 | 3 | 5 |
   Methotrexate | 1 | 1 | 2 |
   Cyclosporin A | 0 | 1 | 1 |
   Angiotensin blocking agents | 9 | 32 | 41 |
   Hydrochloroquine | 7 | 26 | 33 |