Table 2 Genes with concordant progression patterns in human and mouse disease
Progression | GeneSymbol | corHuman | p.Human | corMouse | p.Mouse | MM.magenta |
|---|---|---|---|---|---|---|
+ | ADA | 0.57 | 5.5 × 10-7 | 0.62 | 9.2 × 10-4 | 0.70 |
+ | AIF1 | 0.51 | 1.6 × 10-5 | 0.57 | 3.1 × 10-3 | 0.67 |
+ | C1QB | 0.54 | 3.2 × 10-6 | 0.65 | 4.6 × 10-4 | 0.71 |
+ | CASP3 | 0.59 | 1.8 × 10-7 | 0.52 | 8.2 × 10-3 | 0.59 |
+ | CYBB | 0.63 | 1.6 × 10-8 | 0.56 | 3.4 × 10-3 | 0.82 |
+ | ENTPD1 | 0.51 | 1.2 × 10-5 | 0.62 | 8.5 × 10-4 | 0.66 |
+ | GZMA | 0.63 | 1.7 × 10-8 | 0.70 | 1.0 × 10-4 | 0.72 |
+ | GZMK | 0.61 | 5.8 × 10-8 | 0.55 | 4.1 × 10-3 | 0.63 |
+ | HLA-DQB1 | 0.53 | 6.0 × 10-6 | 0.65 | 5.0 × 10-4 | 0.48 |
+ | HLA-DRB1 | 0.53 | 5.9 × 10-6 | 0.74 | 2.6 × 10-5 | 0.89 |
+ | IFIT1 | 0.59 | 2.6 × 10-7 | 0.59 | 1.9 × 10-3 | 0.43 |
+ | ITGAX | 0.51 | 1.2 × 10-5 | 0.63 | 6.8 × 10-4 | 0.68 |
+ | LY86 | 0.58 | 4.4 × 10-7 | 0.53 | 6.4 × 10-3 | 0.78 |
+ | PLEKHA2 | 0.63 | 1.5 × 10-8 | 0.52 | 7.1 × 10-3 | 0.87 |
+ | STAT1 | 0.67 | 7.2 × 10-10 | 0.64 | 5.2 × 10-4 | 0.60 |
+ | TLR7 | 0.63 | 1.6 × 10-8 | 0.63 | 6.6 × 10-4 | 0.61 |
- | ALDH3A2 | -0.50 | 1.8 × 10-5 | -0.63 | 8.0 × 10-4 | -0.64 |
- | ANGPTL4 | -0.50 | 1.9 × 10-5 | -0.58 | 2.6 × 10-3 | -0.40 |
- | ATP1B1 | -0.56 | 1.0 × 10-6 | -0.58 | 2.5 × 10-3 | -0.62 |
- | CPT1A | -0.54 | 4.0 × 10-6 | -0.76 | 8.7 × 10-6 | -0.55 |
- | FAF1 | -0.54 | 4.1 × 10-6 | -0.55 | 4.5 × 10-3 | -0.58 |
- | NEO1 | -0.52 | 9.6 × 10-6 | -0.53 | 6.9 × 10-3 | -0.47 |
- | PALMD | -0.50 | 2.2 × 10-5 | -0.64 | 6.1 × 10-4 | -0.65 |
- | PDHA1 | -0.58 | 3.9 × 10-7 | -0.63 | 8.0 × 10-4 | -0.71 |
- | PPFIBP2 | -0.56 | 1.2 × 10-6 | -0.57 | 3.2 × 10-3 | -0.48 |