OPN gene polymorphisms influence the risk of knee OA and OPN levels in synovial fluid in a Chinese population

Table 4 Genotype and the radiographic severity in patients with OA

Genotype		KL = < 3, number of patients	%	KL > 3, number of patients	%	Global P-value	Adjusted OR	95% CI		Adjusted P-value
-156/G/GG	GG	92	26.21	91	22.81	0.462	1
	GGG	166	47.29	206	51.63		0.787	0.564	1.178	0.223
	GGGG	93	26.50	102	25.56		0.916	0.638	1.376	0.653
	G	350	49.86	388	48.62		1
	GG	352	50.14	410	51.38		0.934	0.786	1.186	0.648
-443C/T	CC	88	25.07	79	19.80	< 0.001	1
	CT	176	50.14	188	47.12		0.816	0.537	1.264	0.352
	TT	87	24.79	132	33.08		0.664	0.365	0.879	0.011
	C	352	50.14	346	43.36		1
	T	350	49.86	452	56.64		0.659	0.647	0.948	0.008
-66T/G	TT	97	27.64	91	22.81	0.462	1
	TG	158	45.01	191	47.87		0.865	0.587	1.234	0.174
	GG	96	27.35	117	29.32		0.757	0.438	0.944	0.023
	T	332	47.29	373	46.74		1
	G	370	52.71	425	53.26		0.7326	0.668	0.973	0.017

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