Table 4 Association between joint space narrowing (JSN) progression and bone marrow lesion (BML) volume change
| Â | Â | JSN progression | Â | Â | |
|---|---|---|---|---|---|
Rank for change in BML volume | Median (min, max) cm 3 | No | Yes | Odds ratio* (95% CI) | Overall P value |
Medial or lateral JSN progression (n = 350) | Â | Â | Â | Â | |
BML regression (n = 87) | -0.97 (-12.59, -0.46) | 66 (76%) | 21 (24%) | 1.86 (0.96 to 3.60) | Â |
No to minimal BML change (n = 176) (middle two quartiles collapsed) | -0.05 (-0.46, 0.24) | 150 (85%) | 26 (15%) | Reference | 0.11 |
BML progression (n = 87) | 0.73 (0.25, 10.02) | 66 (76%) | 21 (24%) | 1.79 (0.92 to 3.46) | Â |
Medial JSN progression (n = 301) | Â | Â | Â | Â | Â |
Medial TF BML regression (n = 75) | -0.97 (-9.48, -0.46) | 53 (74%) | 19 (26%) | 3.07 (1.44 to 6.57) | Â |
No to minimal medial TF BML change (n = 151) (middle two quartiles collapsed) | -0.08 (-0.46, 0.23) | 130 (89%) | 16 (11%) | Reference | 0.01 |
Medial TF BML progression (n = 75) | 0.65 (0.23, 4.76) | 58 (81%) | 14 (19%) | 1.62 (0.73 to 3.61) | Â |