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Table 1 Clinical characteristics of patients with sera included in the cohort

From: The influence of cathelicidin LL37 in human anti-neutrophils cytoplasmic antibody (ANCA)-associated vasculitis

 

Crescentic-positive AAV

Crescentic-negative AAV

Without renal biopsy

Total

15

25

45

Male/female

7/8

9/16

19/26

Age (years)

61 (8 to 78)

44 (7 to 76)

55 (20 to 78)

MPO-positive

14

22

40

Protease 3-positive

2

4

5

Complement 3 (g/l)

0.68 (0.44 to 1.18)

0.95 (0.06 to 1.83)

0.80 (0.36 to 1.99)

Serum creatinine (μmol/l)

736.5 (147.6 to 1,316) ##,*

165.0 (35.2 to 812.4)

381.1 (39.3 to 881)

24-hour proteinuria (g/24 hours)

0.47 (0.17 to 3.58)

0.83 (0.3 to 6.4)

1.80 (0.01 to 7.8)

  1. Data presented as number or median (range). AAV, anti-neutrophil cytoplasmic antibody-associated vasculitis; MPO, myeloperoxidase. ##Difference between the crescentic-positive AAV patients and crescentic-negative AAV patients (P < 0.01). *Difference between the crescentic-positive AAV patients and AAV patients without a renal biopsy (P < 0.05).Note: Each group had one patient shown double positive MPO- and PR3- ANCA in crescentic-positive AAV and crescentic-negative AAV, respectively.
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Arthritis Research & Therapy

ISSN: 1478-6362

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