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Table 1 Demographic, clinical and histological characteristics of the patient cohort

From: Efficacy and safety of rituximab treatment in early primary Sjögren's syndrome: a prospective, multi-center, follow-up study

Treatment group

 

DMARDs

RTX

Number of patients

22

19

Age (years)

43 (30 to 56)

40 (27 to 53)

Sex (female)

22 (100%)

18 (94.7%)

Disease duration (months)

14 (7 to 21)

13 (6 to 20)

Parotid gland enlargement

18 (81.8%)

16 (84.2%)

Cutaneous vasculitis

2 (9.0%)

3 (15.7%)

Pulmonary involvement

1 (4.5%)

1 (5.2%)

Neurological involvement

3 (13.6%)

2 (10.5%)

Renal involvement

0 (0%)

0 (0%)

Autoimmune cytopenia

7 (31.8%)

8 (42.1%)

Myositis

0 (0%)

0 (0%)

Arthritis.

11 (50%)

9 (47.3%)

Lymphadenopathy

15 (68.1%)

17 (89.4%)

ESSDAI

19.8 (6 to 41)

20.3 (6 to 41)

Prednisonea

22 (12.5)

19 (12.5)

DMARDs (HCQ/MTX/CsA)

22 (15/13/8)

0 (0/0/0)

Chisholm and Mason score ≥3

22

19

Focus score

1.8 (1 to 3.3)

1.8 (1 to 3.4)

  1. Data presented as mean (range) or number (%) unless otherwise stated. CsA, cyclosporine; DMARDs, disease-modifying anti-rheumatic drugs; HCQ, hydroxychloroquine; MTX, methotrexate; RTX, rituximab. aData presented as number of patients (mean dose in milligrams).